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The Kemp Lab at Wright State University
Research
Understanding the DNA damage response in human cells and skin
ATR kinase function in non-replicating cells
How does ATR kinase regulate cellular responses to DNA damage in non-replicating cells? How do ATR kinase inhibitors impact mutagenesis and carcinogenesis?
Mutagenic DNA replication in geriatric human skin
Why do most non-melanoma skin cancers occur in people over the age of 60? How does insulin-like growth factor (IGF-1) influence keratinocytes responses to UVB radiation?
Biology of sedDNAs in human cells and skin
Can the sedDNAs products of nucleotide excision repair be used to measure DNA repair activity in human skin? What is the fate of the sedDNAs?
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